Endocrine Abstracts

Irisin is an adipomyokine produced during physical activity and implicated in the browning of adipose tissue. Existing evidence suggests an inverse relationship between irisin plasma levels and adverse metabolic outcomes; however, the exact impact of diet on irisin levels remains unclear. We aimed to assess the effects of two dietary patterns, Christian Orthodox fasting (OF) and 16:8 time-restricted eating (TRE), on irisin concentrations among overweight, metabolically healthy...

Background: Data on the effects of different dietary patterns on free 25-hydroxyvitamin D [25(OH)D] and vitamin D binding protein (VDBP) concentrations are scarce. Our objective was to prospectively assess changes over time in these parameters and possible correlations with diet composition among overweight adults who followed a pescatarian Orthodox intermittent fasting (OF) regimen and controls who followed a low-fat 12:12 diet for 7 weeks.Methods: Tota...

Background: Previous research has demonstrated positive effects of Orthodox fasting (OF) and time restricted eating (TRE) on body weight (BW). However, little is known about the late, metabolic effects of the two diets.Methods: 29 overweight adults followed a hypocaloric diet based on OF. A hypocaloric, TRE plan (eating between 08:00 to 16:00 h) was followed by 16 BW-matched participants. Anthropometric, glycemic and inflammation markers and serum lipids...

Background: Orthodox fasting (OF), a periodical vegetarian subset of the Mediterranean diet, has been shown to exert beneficial effects on human health. Athonian fasting is a pescetarian OF variation, where red meat is restricted throughout the year. Previous studies have examined the OF nutritional synthesis and health impact in general population fasters (GF) and Athonian monks (AM), separately. This is the first study to comparatively evaluate the characteristics and effect...

BackgroundOrthodox religious fasting (OF) is a variation of the classical Mediterranean Diet during which meat and other animal products are restricted, whereas fish are occasionally and sea food are always allowed. The aim of this prospective study was to assess sex-specific differences in changes of lipid concentrations in a cohort of metabolically healthy adults following OF and investigate a potential role of vitamin D status in mediating these varia...